What is H4CBD? Exploring the Potency, Benefits and Applications

Skriven av: Jans Beloglazovs



Tid att läsa 6 min


H4CBD (Hexahydrocannabidiol) is an intriguing cannabinoid that's recently caught the attention of the medical and scientific communities. Cannabinoids are active compounds found in cannabis plants, with THC and CBD being the most well-known. However, H4CBD is a novel and promising compound that merits a closer examination.

What is H4CBD?

Hexahydrocannabidiol (H4CBD), alternatively known as hydrogenated CBD, is a lab-created synthetic cannabinoid. Originating from CBD, this unique compound is synthesized through advanced chemical techniques, enabling it to effectively interact with the endocannabinoid system. Crafted in laboratories, H4CBD is not a new entrant in the cannabinoid market; its synthesis was first achieved in the 1940s.

For over 80 years, H4CBD has been known to the scientific community, yet it only recently started gaining traction among researchers and cannabinoid enthusiasts. The past two decades have seen a significant surge in the popularity of cannabinoids, thanks to their promising potential and varied applications. This increased interest has cast a spotlight on previously known compounds like H4CBD, driving renewed investigation into their properties and benefits.

Though H4CBD and cannabidiol (CBD) display shared characteristics, these are different compounds in essence. The commonality between the two is cannabidiol, but it’s crucial to highlight that H4CBD is a hydrogenated derivative of traditional CBD. Uniquely, H4CBD engages with the CB1 cannabis receptor, creating a mild recreational effect that sets it apart from its CBD counterpart.

Nine Realms H4CBD liquid oil close up

Key Takeaways:


Discovery of H4CBD: Hexahydrocannabidiol (H4CBD), a synthetic cannabinoid derived from CBD through advanced chemical synthesis, has been known to the scientific community since the 1940s but has only gained significant attention in recent years due to the growing interest in cannabinoid research and potential therapeutic applications.


Comparison to CBD: While sharing some characteristics with CBD, H4CBD is distinct in its interaction with the CB1 cannabis receptor, offering a mild recreational effect, which differentiates it from the non-psychoactive nature of traditional CBD, highlighting the diversity and potential versatility of cannabinoids.

Potential Benefits of H4CBD

Easing Anxiety and Stress

H4CBD may help in calming the mind and promoting a sense of relaxation without the same euphoria associated with THC.

Boosting Mood

The compound offers a mildly psychoactive alternative to other cannabinoids, allowing users to enjoy the mood-improving benefits in a low potency form.

Alleviating Discomfort

The unique properties of H4CBD not only make it an intriguing option for those seeking to diminish pain but also spotlight its prospective utility in the broader realm of pain management and relief strategies.

Lifting Depression

By potentially stabilizing mood and promoting a sense of well-being, this compound may aid individuals in navigating through the dark clouds of depression.

Female relaxing in waterfall

Further Readings

→ How does H4CBD compare to CBD, THC and other cannabinoids?

→ Why H4CBD is a promising cannabinoid for regular consumption?

"Sit back and relax, literally."

Overheard at Cannafest

H4CBD vs Other Cannabinoids


The main difference resides in their chemical structure and effects. Unlike CBD, which does not produce psychoactive effects, H4CBD can generate a slight feeling of euphoria due to its higher affinity for CB1 receptors in the brain.


While both cannabinoids have therapeutic potentials, their legal statuses, psychoactive properties, and safety profiles differ significantly. H4CBD is less psychoactive, calming effects and is legal in many jurisdictions.


Although H4CBD and HHC are produced in a similar way, they are different substances. HHC is essentially a modified version of THC, whereas H4CBD is a hydrogenated version of CBD, which makes HHC more potent than H4CBD.


Both represent different classes of cannabinoids, with H4CBD being synthetic and THCP being a recently discovered natural cannabinoid. Both have psychoactive effects, with THCP being highly potent in comparison to H4CBD.

Nine Realms H4CBD vape female smoking

Why choose H4CBD Products?

Low Potency

H4CBD has mild psychotropic effects, making it an attractive option for individuals looking for relief without the potent “high”


Stable nature ensures a longer shelf life and consistent performance while maintaining the efficacy and safety

Holistic Benefits

H4CBD interacts with the body's endocannabinoid system to stabilize mood and induce a calming effect

H4CBD Formulation

Best Product for Beginners

Nine Realms VERK Edibles

Introducing our latest offering, the H4CBD edibles "Verk," thoughtfully crafted to enhance focus and diminish anxiety in a gentle, low-potency approach. Nine Realms' "Verk" edibles provide a powerful combination of sweet and sour flavors while instilling a low-potent effect.

Enriched with fruity undertones and infused with 30mg H4CBD and 15mg CBG, our edibles serve as an exceptional option for individuals seeking to enhance productivity, minimize distractions, alleviate anxiety, and uplift their mood.
100% Organic & VeganLow PotencyVolume: 10 gummiesLab certified, premium H4CBD, CBGShelf life: 1 year


  • 100% Organic & Vegan
  • Low Potency
  • Volume: 10 gummies
  • Lab certified, premium H4CBD, CBG
  • Shelf life: 1 year

Nine Realms VERK H4CBD Gummies

"It's the perfect blend for those who wish to savor relaxation and taste in every puff."


In summary, THCP emerges as a groundbreaking cannabinoid, setting a new benchmark in the realm of cannabis research and application. Its discovery not only expands our understanding of the cannabis plant's complexity but also opens doors to novel therapeutic possibilities.


Exceptional Potency: THCP is approximately 30 times more potent than THC, offering a powerful option for those seeking significant effects from smaller quantities.


Broad Spectrum of Benefits: From neuroprotection and appetite stimulation to aiding in sleep and reducing muscle spasms, potential benefits signal a promising future in cannabis-based therapies.


Distinguished from Other Cannabinoids: With a unique chemical structure that enhances its interaction with the body's endocannabinoid system, THCP stands out not just in potency but also in its potential for more profound, long-lasting effects compared to THC, HHC, HHCP, and H4CBD.

As the cannabis community continues to explore the depths of this plant's capabilities, the new cannabinoid represents a fascinating chapter in the ongoing journey to understand and harness the full potential of cannabis for human health and wellness.

Discover the full spectrum of possibilities with our carefully curated selection at the Nine Realms store, where every product reflects our dedication to excellence and the latest in cannabinoid research.

A man smoking Nine Realms vape

Author: Jans Beloglazovs

Emerging from Europe's strict cannabis landscape, Jan has become a known figure in the European cannabis industry through vast experience in cannabusiness and a keen understanding of the shifting trends in Europe. Co-founding the Nine Realms cannabis brand, he leverages his expertise to advocate for progressive cannabis policies and educate a broad audience.

Frequently Asked Questions

Which method of consumption is better?

The preferred method of consuming H4CBD, like traditional CBD, depends on personal preference, desired effects, and convenience. 

Oils and tinctures allow for precise dosing and can be taken sublingually for a relatively quick onset of effects. 

Capsules and edibles offer convenience and discretion, with effects that take longer to manifest but also last longer. Topical applications are ideal for localized relief. 

Vaping provides the quickest onset of effects, but not everyone may be comfortable with inhalation. Assess your lifestyle and needs to choose the method that best suits you.

What is the perfect dosage for a beginner?

For beginners, it's advisable to start with a low dosage of H4CBD and gradually increase it as needed, based on your body's response. Since H4CBD is relatively new and might have enhanced potency due to its hydrogenated structure, starting with a dose lower than what you might use for traditional CBD could be wise. 

For example, if you're new to CBD, starting with 5-10 mg of H4CBD and assessing your tolerance before increasing the dose is recommended. Keep in mind, the optimal dose varies from person to person due to factors like body weight, metabolism, and the condition being addressed.

What kind of effect should I expect?

H4CBD is expected to offer similar benefits to CBD, such as relief fromanxiety, stress, and pain, but potentially with greater bioavailability or potency due to its hydrogenated form. 

This means you might experience these effects more pronouncedly or quickly. However, unlike THC-containing products, H4CBD should not induce psychoactive effects, allowing you to remain clear-headed.  Still, individual experiences can vary based on dosage, method of consumption, and personal body chemistry.

Can I incorporate H4CBD into my daily routine?

Yes, H4CBD can be incorporated into your daily routine, similar to how you might use CBD. Due to its non-psychoactive nature, it can be used at any time of the day to potentially aid with stress, anxiety, inflammation, and pain without impacting cognitive functions. 

Whether you prefer to start your day with a dose to foster calmness and focus or use it in the evening to unwind and promote better sleep, H4CBD can be a versatile addition to your wellness regimen.